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Freedom House Healthcare Consulting

FH Healthcare Consulting provides services to Life Sciences organizations helping them optimize theirmarket access and reimbursement, leveragingHEOR tools: that is,achievable price, time to market and patient population size.

Its Founder and Managing Director, Andrea Latour, has a unique blend ofstrategy & commercial,market access & pricing, andHEOR & evidence generation experience, from many years in Industry and Consulting roles, across European and APAC markets.

Our Services

Market Access

  • Market/payer landscape assessment
  • Stakeholder/KOL mapping
  • New product planning
  • Value proposition development
  • GVD/CVD development and adaptation
  • Payer engagement

Pricing

  • Pricing research
  • Willingness-to-pay (Gabor-Granger/Van Westendorp)
  • Payer's analogues & precedents
  • Economically justifiable price (EJP)
  • HE analysis integration
  • Access schemes, RSAs, MESs

HTA

  • HTA roadmapping
  • Reimbursement dossier development
  • Dossier review
  • Targeted literature reviews
  • Stakeholder input collection
  • Patient organization engagement

HE (Health Economics)

  • Model development (CUA, CEA, CMA)
  • Decision Tree, Markov, Partition Survival
  • BIA: Financial & Outcome-based
  • Model adaptation
  • COI/BOI studies
  • Bucher ITC & Local HE studies

OR / RWE

  • Evidence gaps analysis
  • Evidence generation planning
  • Costing and MRU studies
  • Ad boards, Delphi Panels
  • Publications & Literature reviews
  • Evidence dissemination

Our Experience

Projects & Similar

TypeAssignmentClient / Year
Market access, pricing and policy Pricing analysis for new launch in mantle cell lymphoma based on NICE analogues and IRPLarge Pharma, 2015
Market access, pricing and policy KOL and patient org mapping and engagement in collaboration with MAF, and stakeholder input to NICE appraisal for key asset in MCLLarge Pharma, 2015
Market access, pricing and policy Pricing strategy and access schemes option identification for new product in CLL in Australia (PBAC)Large Pharma, 2016-2017
Market access, pricing and policy Analysis of achievable price for key asset in CLL, in reference to SOC, new assets, analogues and precedents, and IRP, in AustraliaLarge Pharma, 2017-2018
Market access, pricing and policy Quantifying affording population in South-Asian markets for ultra-high, high and medium price medicines, and identifying key applicable public, private and alternative funding mechanisms Med-size Pharma, 2020
Market access, pricing and policy KOL mapping and engagement recommendations for minimal residual disease (MRD) in haematology in Australia and JapanSmall/Mid-size Pharma 2020
Market access, pricing and policy Access pathway mapping for genome testing in NICU patients with rare genetic diseases, in JapanMid-size MedTech, 2020
Market access, pricing and policy White paper on key issues and policy developments in access to high-cost oncology medicines in developed markets and in AsiaLarge Pharma, 2020
Market access, pricing and policy PharEast Conference - Panel: Adapting to the changing market access landscapePharEast Conference, 2021
Market access, pricing and policy Challanges and delays in access in mood disorders compared to other TAs globally and recommendations to improve accessLarge Pharma, 2021
Market access, pricing and policy Mapping optimal pathways for regulatory and market access for biomarker-based technologies in mood disorders in Australia, China, Japan, Korea and TaiwanLarge Pharma, 2021
Market access, pricing and policy Mapping opportunity for launch in private markets, in terms of market size and maturity, across 40 countries and for partnership with private health insurance providers, ex-USLarge Pharma, 2021
Market access, pricing and policy Landscaping and assessment of bridging strategies for CV outcomes trials and implications to P&R - Playbook and Position paperLarge Pharma, 2022
Market access, pricing and policy Workshop on opportunities for partnership with private health insurance, after scoping for alternative funding mechanismsLarge Pharma, 2024
Health economicsCEM and BIM adaptation for atorvastatin in ItalyLarge Pharma, 2009-2010
Health economicsCEM (Core Diabetes Model) country adaptations and technical reports (European markets) in T2DMLarge Pharma, 2010-2011
Health economicsDevelopment of global CEA and BI models for product in metastatic melanoma, incl survival analysisLarge Pharma, 2011-2013
Health economicsCEA and BI global model adaptation for product in metastatic melanoma - SpainLarge Pharma, 2012-2013
Health economicsBI model development for product in adjuvant melanoma - SwedenLarge Pharma, 2012-2013
Health economicsBudget impact models for NICE and SMC submissions for new treatment in COPDLarge Pharma/MedTech, 2011-2012
Health economicsSLR for SMBG in T2DM, incl search strategy design, search execution, abstract/full-text review and data extraction Large Pharma/MedTech 2012
Health economicsSLR and CEM development for product in wet age-related macular degeneration Large Pharma, 2012
Health economicsCEM for new product launch in NASH focusing on hepatic and CV eventsMid-size Pharma, 2012-2013
Health economicsCEM and BOI model adaptations for new long-acting injectable in schizophrenia in the UKLarge Pharma, 2013
Health economicsCMA of new fixed-dose combination in HIV compared to single agents and SOC in Scotland and WalesLarge Pharma, 2013
Health economicsCEM development and ITC/MAIC for major new asset in mantle cell lymphoma, for NICE submissionLarge Pharma, 2014-2015
Health economicsVisiting lecturer to Cambridge uni MSC students on CEA and BIACambridge uni, 2015
Health economicsCEA for new product vs SOC, incl companion diagnostics, in CLL in AustraliaLarge Pharma, 2016-2017
Health economicsCMA for new product vs Key comparator targeted therapy, with different MOA and treatment duration, in CLL, in Australia Large Pharma, 2017-2018
Health economicsOutcomes-based BIM adaptation and value proposition development for TAVI in APAC marketsLarge MedTech, 2018
Health economicsCEM and BIM model adaptations for Transarterial Radio embolization in HCC, in APAC marketsMid-size MedTech, 2019
Health economicsBudget impact analysis and cost-based value proposition for CAR-T + publication, in SingaporeLarge Pharma, 2019
Health economicsModel adaptations for a new asset in neuroendocrine tumours in Taiwan, Korea, Hong Kong and SingaporeLarge Pharma, 2019-2020
Health economicsCost of illness model development in haemophilia A, focusing on prophylaxis and treatment of bleed events, in APAC marketsLarge Pharma, 2019-2020
Health economicsCEM adaptation for prostate cancer drug in TaiwanLarge Pharma, 2020
Health economicsTargeted lit review, KOL interviews and CEM & BIM adaptation for product in CKD in IndonesiaLarge Pharma, 2020
Health economicsCEM re-development for genome testing in NICU patients with rare genetic diseases, in JapanMid-size MedTech, 2020
Health economicsCEM development for different management options for malaria in UgandaLarge Pharma/MedTech 2020
Health economicsCMA and BIA for introduction of new vaccine in Middle-East marketsLarge Pharma, 2020
Health economicsISPOR presentation: Uniqueness and challenges of economic evaluations in oncology. Drugs, devices and diagnosticsISPOR oral presentation, 2020
Health economicsISPOR presentation: Modelling oncology from patient-level data: parametric models and extrapolationsISPOR oral presentation, 2020
Health economicsPragmatic CEM development to support value proposition of reduced resource consumption with bleed prophylaxisLarge Pharma, 2020-2021
Health economicsModel adaptations and reports for innovative product in wound care in APAC markets, incl SEAMid-size MedTech, 2020-2021
Health economicsModel adaptation for new PARP inhibitor in ovarian cancer in SingaporeLarge Pharma, 2021
Health economicsCommercial forecasting and budget impact analysis for a new CAR-T incl sequential algorithm and cannibalization, in Australia, China and JapanLarge Pharma, 2022
HTABIA section of NICE submission for product in wet age-related macular degeneration Large Pharma, 2012
HTAHTA submission for new formulation of existing products (various) in HIV - SMC Scotland and AWMSG WalesLarge Pharma, 2013-2014
HTAHTA submission for new fixed dose combination in HIV - SMC Scotland and AWMSG WalesLarge Pharma, 2013-2014
HTAHTA submission for major blockbuster launch in mantle cell lymphoma - NICE EnglandLarge Pharma, 2015-2016
HTAHTA submission for major launch in chronic lymphocytic leukaemia, submission and re-submissions - PBAC AustraliaLarge Pharma, 2016-2018
HTAHTA strategy and dossier writing for Transarterial Radio embolization in HCC, in Korea and TaiwanMid-size MedTech, 2019
HTAHTA strategy and execution for a new asset in neuroendocrine tumours in Taiwan, Korea, Hong Kong and SingaporeLarge Pharma, 2019-2020
HTALed the negotiation process between the Agency for Care Effectiveness (ACE) and The Singapore Association of Pharmaceutical Industries (SAPI) for the development of the new manufacturer-led HTA submission processACE and SAPI, 2020
HTAACE submissions for PD-L1 inhibitor in two indications, incl model adaptation and targeted lit reviewLarge Pharma, 2022
Outcomes research / RWEResearch and compilation of observational evidence to support value proposition of atorvastatin for regional access in ItalyLarge Pharma, 2009-2010
Outcomes research / RWECosting study for resource utilisation to manage spasticity in multiple sclerosis, incl publicationLarge Pharma, 2011
Outcomes research / RWEIntegrated evidence generation planning as part of cross-functional international team, for new asset and new indications in haematologyLarge Pharma, 2017-2018
Outcomes research / RWEReview of 14 early compounds across TAs for probability of success, on behalf of A*STAR for the Singapore Therapeutic Development Review processSingapore government entity, 2020
Outcomes research / RWECompetitive TPP assessment, clinical and economic evidence gaps analysis for two gene therapies in ophthalmology in Australia, Japan, China and KoreaLarge Pharma, 2021
Outcomes research / RWEQuality of evidence and gap analysis for new asset in SCLC cancer in APAC marketsLarge Pharma, 2021
Outcomes research / RWEEvidence gaps assessment and strategy for tumour agnostic innovative medicine in JapanLarge Pharma, 2021
Outcomes research / RWEMarket access risks & opportunities based on evidence-gap assessment in SCCHN cancer in China, Japan, Australia, Korea and TaiwanLarge Pharma, 2022
Outcomes research / RWEMarket access risks & opportunities based on evidence-gap assessment in SCLC cancer in China, Japan, Australia and KoreaLarge Pharma, 2022
Commercial & Strategy Asia Healthcare conference Panel session: Future of healthcare in AsiaAsia Healthcare conference, 2021
Commercial & Strategy Commercial due diligence for Pharma co acquisition across all TAs in SEA marketsLarge PE firm, 2021
Commercial & Strategy Design and implementation for restructuring of NPP and CEx functions in APACLarge Pharma, 2022
Commercial & Strategy Market entry strategy for conglomerate into Pharma business in VietnamConglomerate
Commercial & Strategy Development of AI-powered 'Patient Intelligence Engine' to predict patient drop-outs and prescribe next-best-action in APACLarge Pharma, 2023
Commercial & Strategy AI-driven customer identification, segmentation and reach in fertility, in TaiwanMid-size Pharma/Consumer Health, 2023
Commercial & Strategy Commercial due diligence for likelihood of success of early stage asset in ovarian cancer in KoreaLarge Pharma, 2024
Commercial & Strategy Market entry opportunity assessment (SEA) and manufacturing plant location assessment (Thailand Vs Indonesia)Small Pharma, 2024
Commercial & Strategy Product, channel strategy for midsize pharma co across SEA and other Asian marketsMid-size Pharma, 2024
Commercial & Strategy Market segmentation and opportunity prioritization on obstructive sleep apnea, in China, Japan and ThailandMid-size MedTech, 2024

Journal Publications

TypeName & InfoLink
Costing studyV Stevenson, A Latour, J Broughton, A Lloyd. Cost of spasticity associated with multiple sclerosis in the UK; presented at the ABN (Association of British Neurologists) Meeting 2011 [J Neurol Neurosurg Psychiatry 2012;83:e1 doi:10.1136/jnnp-2011-301993.192]Available here
HE modellingLatour A, Schweikert B, Desai M. Reduction in costs over two years when treating with darunavir/ritonavir compared to atazanavir/ritonavir in the UK. ISPOR, Milan 2015.Available here
HE modellingIannazzo S, Coco B, Brunetto MR, Rossetti F, Caputo A, Latour A, Espinos B, Bonino F. Individualized treatment of HBeAg-negative CHB using peg-interferon alfa-2a as first-line and week 12 HBV-DNA\HBsAg stopping rule. A cost-effectiveness analysis; published in 'Annuals of Internal Medicine' [PMID: 23486701].Available here
HE modellingS Critchlow, D Lee, A Latour, M Wildgust, J Goldberg, S Rule, M Wang. Modelling the Effectiveness of Ibrutinib Versus Rituximab-Based Chemotherapy Regimens in Relapsed/Refractory Mantle Cell Lymphoma. ISPOR, Vienna 2016.Available here
HE modellingLakhanpal, Latour, Wang, Wang, Budget IMPACT Analysis (BIA) of Introducing Tisagenlecleucel for the Treatment of Patients with Relapsed and Refractory Diffuse Large B-CELL Lymphoma (R/R DLBCL) in Singapore (SG). ISPOR APAC (Virtual) 2020.Available here

FREEDOM HOUSE (FH) - HEALTHCARE CONSULTING PTE. LTD.
133 New Bridge Road #23-09 Chinatown Point, Singapore 059413